Mini-Symposium on Osteoclast Biology
If you are a trainee interested in giving an oral presentation on the subject of osteoclast biology, please submit your abstracts directly to Dr. Manolson and Dr. Voronov. Total of 10 abstracts from trainees will be chosen for 10-minute oral presentations. Please note that submission of an abstract to this satellite meeting is SEPARATE from an abstract submission to CCTC. If you are planning to attend and to present at CCTC 2018, please make sure that you submit your abstract through the CCTC website by March 8th deadline.
| Date: | Wednesday, May 23, 2018 |
| Time: | 13:00 – 17:00 h |
| Location: | Faculty of Dentistry, University of Toronto 124 Edward St. Rm 170 Toronto, ON M5G 1G6 |
Abstract submission to the mini-symposium:
Submission deadline for the Osteoclast Mini-Symposium is March 31, 2018. Abstract instructions are the same as for CCTC 2018 abstracts, maximum 500 words. Please submit your abstract directly to Dr. Morris Manolson (cc. Dr. Voronov) using email addresses below, using a subject line “Abstract for Osteoclast Mini-Symposium”.
| Contact: | Dr. Morris F. Manolson | m.manolson@utoronto.ca |
| Dr. Irina Voronov | irina.voronov@utoronto.ca |
Preliminary schedule:
| 13:15 – 13:45 h |
Registration, coffee and uploading of the talks |
| 13:45 – 14:00 h | Opening remarks: Morrie Manolson |
| 14:00 – 15:15 h |
Trainee presentations |
| 14:00 – 14:15 h | Michèle Roy (Roux lab) – University of Sherbrooke TBC1D25 in human osteoclasts: impact on bone resorption and autophagy |
| 14:15 – 14:30 h | Muthu Lakshmi Muthu (Reinhardt/Komarova Lab) – McGill University Therapeutic potential of osteoclast inhibitory fibrillin-1 fragments |
| 14:30 – 14:45 h | Ruben Philip (Harrison Lab) – University of Toronto Characterizing microtubule organizing centres in osteoclasts |
| 14:45 – 15:00 h | Iris Boraschi-Diaz (Komarova Lab) – McGill University Mechanisms underlying increased osteoclastogenesis in the mouse model of osteogenesis imperfecta due to mutation in collagen type I |
| 15:15 – 15:45 h | Coffee break |
| 15:45 – 16:00 h | Kerstin Tiedemann (Komarova Lab) – McGill University Exosomal release of plastin-2 by breast cancer cells facilitates osteoclast activity in the metastatic bone microenvironment |
| 16:00 – 16:15 h | L Saad (Vacher Lab) – University of Montreal Osteoclastogenesis is modulated by the phosphatase Inpp4b through the PKCb/GSK3b/Nfatc1 pathway |
| 16:15 – 16:30 h | Ralph Zirngibl (Voronov Lab) – University of Toronto Novel c.G630A TCIRG1 mutation causes aberrant splicing resulting in an unusually mild form of autosomal recessive osteopetrosis |
| 16:30 – 16:45 h | Yongqiang Wang (Glogauer Lab) – University of Toronto IL1β and TNFα promote RANKL-dependent adseverin expression and osteoclastogenesis |
| 17:30 – 18:00 h | Walk to Earth Sciences Centre, University of Toronto 5 Bancroft Avenue, Toronto, ON M5S 3J1 (15-20 min walk, weather permitting) |
| 18:00 – 21:00 h | CCTC 2018 Registration & Opening Reception |