Return to CCTC 2014


The 20th Annual Scientific Conference of the CCTS (known also as CCTC 2014) in LONDON / Ontario between 8-10th of June 2014 will consist in three days of oral and poster presentations. A majority of the oral presentations were selected from the submitted abstracts to promote young scientists.

Click to Download the CCTC2014 Program. An early submission deadline of February 28, 2014 exised  to allow students to have an acceptance prior to travel grant application deadlines. Oral and poster sessions in the following research areas will be presented:

  • Stem Cells in Tissue Regeneration and Tissue Engineering
  • Biomechanics, Mechanobiology, and Biomaterials
  • Connective Tissue remodelling
  • Connective Tissue in Disease – Clinical and Fundamental Aspects
  • The Extracellular Matrix in Connective Tissues
  • Genetics of Connective Tissue
  • Bone, Cartilage and Tooth development
  • Cellular Interactions between Connective and other Tissues

Best Talk Award is sponsored by Fibrogenesis & Tissue Repair and Regenerative Medicine Research published byBiomed Central.


Sunday, June 8

5:30-7:30 pm Registration, Delta Armouries Hotel

7:30-10:00 pm Social Event at Milos’ Craft Beer Emporium , 420 Talbot (sponsored by International CCN Society and Department of Dentistry, University of Western Ontario, open especially just for us !)

Monday, June 9

8:00-12:00 pm Registration, Delta Armouries Hotel

8:00-8:30am Coffee available

8:30- 9:00 am Welcoming Remarks

Session 1: Connective Tissue Remodeling #1 (9:00 am‐12:00 pm)

9:00-9:30 am Invited Speaker: Jeff Davidson (Nashville, USA)

9:30-10:30 am Talks chosen from abstracts (10 mins each)

Dominique Behrends (McGill) Defective bone repair in mast cell deficient mice with c-Kit loss of function
Christina Raykha (Western) Identification of β-catenin gene targets by ChIP Sequencing in Dupuytren’s  Disease
Gurpreet S Baht (Toronto) Rejuvenating Fracture Repair
Shabana Amanda Ali (Toronto) Cholesterol homeostasis mediates Hedgehog signaling in chondrocytes and osteoarthritis

10:30-11:00 am “Fruit-tastic” coffee Break and poster viewing

11:00-12:30 pm Talks chosen from abstracts (10 mins each)

Kelly Gutpell (Western)
Non-invasive assessment of therapeutic approaches in a murine model of Duchenne muscular dystrophy
Erik Holm (Western) Delineating the role of bone sialoprotein in bone development and mineralization
Luciene Lacroix (Toronto) Osteoclasts from osteopetrotic Tcirg1R740S mice have impaired autophagy and increased mTORC1 activity
Anusha Ratneswaran (Western) PPARdelta promotes the progression of secondary osteoarthritis
H Mohammadi (Toronto) Impact of inelastic behavior of collagen gels on cell mechanosensation
Pascal Morissette Martin (Laval) Tissue-engineered biological dressings for skin wound healing in a murine model of splinted full-thickness defects

12:00-2:00 pm Lunch and poster session #1

Canadian Connective Tissue Society meeting

Session 2: The extracellular matrix in connective tissue (2:00-3:30 pm)

2:00-2:30 pm Invited Speaker: Bruce Riser (Chicago, USA)

2:30-3:00 pm Invited Speaker: Dieter Reinhardt (Montreal, Canada)

3:00-3:30 pm Talks chosen from abstracts (10 mins each)

Dirk Hubmacher (Cleveland Clinic) Limb-specific deletion of Adamtsl2 in mice leads to brachydactyly and joint malformations: A model system for human acromelic dysplasias
Matthew Riopel (Western) Conditional β1 integrin-deficient mice display impaired pancreatic function and architecture

3:30-4:00 pm “Energy” coffee Break

Session 3: Biomechanics, Mechanobiology and Biomaterials (4:00-6:00 pm)

4:00-4:30 pm Invited Speaker: Jim Johnson (London, Canada)

4:30-6:00 pm Talks chosen from abstracts (10 mins each)

A.L. Ménard (Montreal) Bone growth is still active following removal of static compression on the growth plates
Kevin Middleton (Toronto) Development of a Microfluidic System to Investigate Bone Cell Signaling
Rosa Kaviani (Montreal) Effects of Type, Magnitude and Frequency of in vitro Compression on the Viability of Growth Plate Chondrocytes
Benjamin Wheal (Western) Subcellular calcium signalling encodes directional preference during osteoclast migration
Yohannes Soenjaya (Western) Characterization of the Bone Sialoprotein Null (Bsp-/-) Mice Mandibular Phenotype: The Influence of Mechanical Force in Inducing Mandibular Defects
Chao Liu (Toronto) Mechanical Regulation of Osteocyte Responses to Microdamage in vitro

7:30 PM Gala Dinner Delta Armouries
(Invited speaker A. Robin Poole – Montreal, Canada)
Sponsored by IDI In Bone and Joint Health at the University of Western Ontario

Tuesday, June 10

Session 4: Bone, cartilage and tooth development

8:00-8:30 am Coffee available

9:00-9:30 am Invited Speaker Speaker: Michael Kelley (Durham, USA)

9:30-10:30 am Talks chosen from abstracts (10 mins each)

Daniel Lorusso (Western)
A microfluidic chamber for live cell imaging during fluid shear
Emerson Krock (McGill) Painful degenerating intervertebral discs induce neuroplasticity by actively releasing nociceptive factors
Jake Bedore (Western) Assessing the effect of notochord-specific CCN2 deletion on intervertebral disc degeneration and behaviour associated with back pain
Bashar Alkhatib (McGill) Acute mechanical injury to the human intervertebral disc initiates events implicated in disc degeneration
Chan Gao (McGill) Parathyroid hormone-related peptide (PTHrP) pellet as a preventative treatment for scoliosis
Karina Zeyer (McGill) The RGD cell binding site in fibrillin-1 regulates miRNA expression

10:30-11:00 am “Fruit-tastic” coffee Break and poster viewing

11:00-12:30 pm Talks chosen from abstracts (10 mins each)

Jelena Djokic (McGill) Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly
Amani Hassan (Montreal) Estrogen receptor status and transcriptome profiling of genes regulated by 17-beta estradiol in human osteoblasts derived from idiopathic scoliosis patients
Sally Hu (Toronto) Investigating effects of novel conjugate drugs for the treatment of osteoporosis
Iris Boraschi (McGill) Interactions of osteoclasts with collagen type I
Heena Kumra (McGill) The role of fibronectin as a master organizer of tissue in vivo
Nguyen Hong Phuc Pham (McGill)
Mouse fibrillins are differently organized in microfibrils compared to human fibrillins
12:30-2:00 pm Lunch and Poster session #2

Session 5: Connective tissue remodelling #2

2:00- 2:30 pm Speaker: Lina Dagnino (London, Canada)

2:30-3:15 pm Talks chosen from abstracts (10 mins each)

N. Talale (Toronto)  Expression of α-SMA governs the stemness and fibrotic fate of mesenchymal stromal cells.
Haoran Li (Toronto) Nanoparticle conjugated anti-microRNA-378a enhances angiogenesis and wound healing in a murine model
Matthew McCann (Western) Whole body vibration results in degeneration of the intervertebral disc and knee joint in a mouse model: is fibrocartilage the culprit?

3:15-4:00 pm Closing remarks/ Oral presentation and poster awards sponsored by Springer and Biomed Central


CCTC 2014 Abstracts Password Protected

Abstracts 2014 password protected (for journal submission protection)

Abstracts 2014 password protected (for journal submission protection)

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