DOWNLOAD PDF PROGRAM PDF FILE: CCTC 2017 Program
THURSDAY, May 18
6:00- 9:00pm Registration, Reception and Refreshments
FRIDAY, MAY 19
7:45 – 8:30am Light Breakfast
7:45 – 3:00pm Registration Desk Open
8:30 – 8:45am Welcome Remarks from Co-Chairs of Organizing Committee.
Anie Philip, McGill University
Stephane Roy, Université de Montréal
SESSION I – BONE AND CARTILAGE DISEASE: MECHANISTIC AND REGULATORY ASPECTS
Moderators: Lauren Flynn and Jean Vacher
8:45 – 9:30am Keynote Lecture: “Influence of Surface Topography and Micromotion on Healing at the Bone-Implant Interface.”
Antonio Nanci, Université de Montréal, Montreal, QC
9:30 – 10:30am Selected Abstracts
9:30am “MicroRNA-34a: Role In The Development Of Osteoarthritis During Obesity.”
Helal Endisha, University of Toronto, ON.
9:40am “Cartilage-Specific ULK-1 Knockout Induces Inhibition Of Autophagy Pathway And Increased Cartilage Destruction With Secondary Inflammatory Effects On Synovium.”
Brain Wu, Krembil Research Institute, University Health Network, Toronto, ON.
9:50am “High-Fat Diet-Induced Acceleration Of Osteoarthritis Is Associated With Sustained Metabolite Signature Regulated By Leptin/Autotaxin Pathway.”
Poulami Datta, University of Toronto, ON.
10:00am “Modulation of Parathyroid Hormone Receptor 1 Signaling By Extracellular Nucleotides.”
Brandon H. Kim, Schulich School of Medicine & Dentistry, Western University ON.
10:10am “Role of Osteoblast Menin In Bone Metabolism: In-Vivo Studies Of Knockout Mice.”
Jad Abi-Rafeh, Division of Experimental Medicine, McGill University, Montreal, ON.
10:20am “Mechanically-Evoked ATP Release Is Regulated By Facilitated Membrane Resealing In Murine Osteoblasts.”
Nicholas Mikolajewicz, Shriners Hospital for Children, McGill University
10:30 – 10:45am Coffee and Networking Break
SESSION II – CONNECTIVE TISSUE DISEASE CHARACTERISTICS: CLINICAL AND FUNDAMENTAL ASPECTS
Moderators: Fackson Mwale and David O’Gorman
10:45 – 11:15am Invited Talk: “Elucidating the Role of POC5 in Idiopathic Scoliosis.”
Florina Moldovan, Université de Montréal, CHU Sainte-Justine Research Center, Montreal, QC
11:15- 12:15pm Selected Abstracts
11:15am “Characterizing Degeneration Of Facet Joint Cartilage In Adolescent Idiopathic Scoliosis.”
Daniel Bisson, McGill University & Shriner’s Hospital for Children, Montreal, QC.
11:25am “Effect Of Tissue-Specific Extracellular Matrix On The Adipogenic And Chondrogenic Differentiation Of Human Adipose-Derived Stromal Cells.”
Danielle Heinbuch, University of Western Ontario, London, ON.
11:35am “Characterization Of Proteins In The Specialized Basal Lamina Associated With The Tooth.”
Aurélien Fouillen, Université de Montréal, Montréal, QC.
11:45am “Use Of Unfixed Histology To Visualize And Characterize Meniscus Inter-Tie Coil Structures In Intact Knees And Knees Following Surgical Procedures.”
Colleen Mathieu, Ecole Polytechnique de Montreal, Montreal, QC.
11:55am “Role Of Phex-Fgf23 Axis And Γ-Carboxylation On Vascular Calcification Caused By Mgp Deficiency.”
Abhinav Parashar, McGill University, Montréal, QC.
12:05pm “Male Mice Are More Susceptible To Whole-Body Vibration Induced Joint Damage Than Age-Matched Female Mice.”
Geoffrey Kerr, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON.
12:15 – 2:00pm LUNCH/ Poster Viewing
12:15 – 2:00pm CCTS BOARD MEETING
SESSION III – BONE AND CARTILAGE: GENETIC AND DEVELOPMENTAL ASPECTS
Moderators: Svetlana Komarova and Showan N Nazhat
2:00 – 2:30pm Invited Talk: “Building articular cartilage: A new blueprint.”
Rebekah S. Decker, Genomics Institute of the Novartis Research Foundation
2:30 – 3:00pm Selected Abstracts
2:30pm “Identifying Gli Transcriptional Targets In Chondrosarcoma Using Next Generation Sequencing.”
Amanda Ali, University Health Network, Toronto, ON.
2:40pm “Undercarboxylated Osteocalcin And Metabolic Phenotype In The Mouse Model Of Osteogenesis Imperfecta.”
Iris Boraschi-Diaz, Shriners Hospital for Children, McGill University, Montreal, QC.
2:50pm “Biological Repair Of Osteoarthritic Cartilage Using Short Link N.”
Muhammad Albesher, Lady Davis Institute for Medical Research, McGill University, Montreal, QC.
3:00 – 3:15pm Coffee and Networking Break
SESSION IV – Selected Abstracts
Moderators: Rebekah S. Decker and Morris Manolson
CONNECTIVE TISSUE REPAIR AND FIBROSIS: CELLULAR AND MOLECULAR ASPECTS
3:15pm “Toll-Like Receptor Activation Induces Human Intervertebral Disc Degeneration.”
Emerson Krock, McGill University, Montreal, QC.
3:25pm “Investigating The Role Of Pannexin 3 As A Regulator Of Intervertebral Disc Health.”
Meaghan E. Serjeant, Schulich School of Medicine and Dentistry, Bone and Joint Institute, University of Western Ontario.
3:35pm “Functional relevance of Fibulin-4 interactions with latent transforming growth factor beta binding protein- 4 in the context of fibronectin and fibrillin-1.”
Heena Kumra, McGill University, Montreal, QC.
BONE AND CARTILAGE DISEASE: TRANSLATIONAL AND CLINICAL ASPECTS
3:45pm “Synovial Membrane Nerve Fiber Density Decreases With Osteoarthritis In Horses.”
Raymond Pujol, University of Montreal, St. Hyacinthe, QC.
3:55pm “Lactosylceramide Enhances Chondrocytic Differentiation.”
Lilit Antonyan, Research Centre, Shriners Hospitals for Children, McGill University, Montreal, QC.
4:05pm “Novel Electromechanical Arthroscopic Device For The Objective And Quantitative Evaluation Of Cartilage Quality.”
Insaf Hadjab, Institute of Biomedical Engineering, Polytechnique Montreal, Biomomentum Inc.
4:15 – 5:45pm Poster Presentations and Viewing
6:00pm – 9:00pm Reception and Formal Dinner (Ticketed Event)
McGill La Citadel 26th Floor Lounge, 410 Sherbrooke St W, Montreal, QC. H3A 1B3
Keynote Talk: “Mechanistic Modeling: The Pathway to Precision Medicine”
V. A. Shiva Ayyadurai, Chairman and CEO, CytoSolve, Inc.
SATURDAY, MAY 20
8:00 – 9:00am Light Breakfast
8:30 -10:30am Registration Desk Open
8:30 -9:00am CCTS BUSINESS MEETING/GENERAL ASSEMBLY
SESSION V – TISSUES REPAIR, REPLACE OR RE-ENGINEER
Moderators: Rene Harrison and Julie Fradette
9:00 – 9:45am Keynote Talk: “Connective Tissue Signaling Through Cell Adhesions in Matrix Homeostasis and Fibrosis.”
Christopher A. McCulloch, University of Toronto, Toronto, ON
9:45 – 10:15am Selected Abstracts
9:45am “Naturally Derived Microcarriers As Tissue-Specific 3-D Cell Culture Platforms.”
Anna Kornmuller, Western University.
9:55am “T1ρ Mri Detection And Histological Evaluation Of Autologous Nucleus Pulposus Cell-Seeded Hydrogel Delivery To Isolated Human Intervertebral Discs In Dynamic Culture.”
Derek H. Rosenzweig, McGill University, Montreal, QC.
10:05am “Blood And Lymphatic Microvascularization Of Self-Assembled Skin Substitutes Using Primary Human Endothelial Cells.”
Jennifer Bourland, Centre de recherche en organogenese expérimentale de l’Universite Laval / LOEX, Quebec, QC.
10:15 – 10:30am Coffee and Networking Break
10:30 – 11:00am Invited Talk: “Osteogenesis Imperfecta – What causes it? What to do about it?”
Frank Rauch, McGill University, Shriners Hospital for Children, Montreal, QC
11:00 – 11:30am Selected Abstracts
11:00am “Chiral Switching Of Calcium Carbonate Biomineral Induced By A Single Chiral Enantiomer Of Amino Acid.”
Wenge Jiang, McGill University, Montreal, QC.
11:10am “An Injectable Chitosan Scaffold With Mechanical Properties Optimized For IVD Repair.”
Yasaman Alinejad, École de technologie supérieure (ETS), Montréal, QC.
11:20am “Regulation Of Matrix Gla Protein Gene Expression By An Intronic Sequence.”
Jobran Mohammed Moshi, McGill University, Montreal, QC.
11:30 – 12:15pm Invited Talk: “Nuclear receptors in cartilage and osteoarthritis.”
Frank Beier, Western University, London, ON