Return to CCTC 2015



The abstract booklet will not be available during the meeting.

To view or download the booklet

Download the CCTC 2015 Program.

Thursday, May 28, 2015

10:00 am – 12:00 am Optional visit of the LOEX Research Center – registration needed, transport is not provided (located outside the campus of Université Laval, see map)
6:00 pm – 8:00 pm Registration – Vandry Building, Université Laval
7:00 pm – 10:00 pm Cocktail event – Vandry Building, Université Laval

Friday, May 29, 2015

8:00 am – 17:00 pm Registration – Desjardins Building, Université Laval
8:00 am – 8:45 am Breakfast (Grand Salon – Desjardins Building)
8:45 am – 9:00 am Welcome Remarks (Veronique Moulin – Julie Fradette, chairs of CCTC 2015) (Amphitheatre HydroQuébec – Desjardins Building)
9:00 am – 10:33 pm Session 1: Connective Tissue Remodeling ISession chairs:            Boris Hinz & Pardis Pakshir
9:00 am – 9:45 am Invited Speaker: Sylvie Ricard-Blum (IBCP, Lyon, France)“Endostatin, a multifunctional matricryptin at the crossroads of several interaction networks
1          9:45 am      Brandon H Kim (Western University, London)“M-CSF induces redistribution of ezrin-radixin-moesin proteins in migrating osteoclasts.
2          9:57 am      Sotcheadt Sim (École Polytechnique, Montreal)“Wound Healing Revealed by a Novel Automated Indentation Technique.
3        10:09 am      Jake Bedore (Western University, London)“Assessing the effect of notochord-specific CCN2 deletion on intervertebral disc degeneration and behaviour associated with back pain.
4        10:21 am      Julia M Pasquale (University of Toronto, Toronto)“Why do only some women develop postmenopausal osteoporosis?
10:33 am – 11:03 am Coffee Break and Poster viewing (Grand Salon)
11:03 am – 12:15 pm Session 2: Connective Tissue Remodeling IISession chairs:            Stephen Sims & Noelle Ochotny
5        11:03 am      Matthew Tsang (Western University, London) “Investigating the mechanisms of formation and myofibroblastic differentiation of skin-derived precursors.
6        11:15 am      Ryan J Beach (Western University, London) “Role of subcellular calcium elevation in polarization of osteoclasts toward the chemoattractant M-CSF.
7        11:27 am      Nuno M Coelho (University of Toronto, Toronto)“Discoidin Domain Receptor 1 Mediates Collagen Remodeling By Compaction and Internalization.
8        11:39 am      Yongqiang Wang (University of Toronto, Toronto)“Adseverin Mediates Alveolar Bone Loss Associated with Inflammation.
9       11:51 pm      Sally Esmail (University of Toronto, Toronto)“Elucidating where and why the V-ATPase “a” subunit isoforms a1, a2, and a4 are glycosylated.
10       12:03 pm      Heena Kumra (McGill University, Montreal)“Synergistic effects of cellular and plasma fibronectin in tissue organization in vivo.
12:15 am – 2:00 pm Lunch and poster session I (evaluation for even number posters only)(Grand Salon)
Canadian Connective Tissue Society board meeting – Room 3425
2:00 pm – 2:30 pm In memoriam to Dr. Cy Franck : Hani El-Gabalawy (Scientific Director of the Institute of Musculoskeletal Health and Arthritis, Canadian Institutes of Health Research)“Cy Frank’s legacy and IMHA strategic plan”
2:30 pm – 4:00 pm Session 3: Musculoskeletal System ISession chairs:            Lisbet Haglund & Emerson Krock
2:30 pm – 3:00 pm Invited Speaker: Guillaume Grenier (Université de Sherbrooke, Sherbrooke, QC)“Microenvironment influence on skeletal muscle progenitor cells
11         3:00 pm      Derek H Rosenzweig (McGill University, Montréal)“An ex vivo model for dynamic culture and tissue repair of human intervertebral disc degeneration.
12         3:12 pm      Sam Si-Hyeong Park (University of Toronto, Toronto) “Intramedullary Wire Fixation of Bone Allograft for Reconstruction of Critically-Sized Radius Segmental Defect in a New Zealand White Rabbit Model.
13         3:24 pm      Noelle Ochotny (Western University, London) “Fluid Flow-Induced Migration of Osteoclasts: Crawling Against the Tide.
14         3:36 pm      Juliana Marulanda (McGill University, Montreal)“Role of Matrix Gla Protein in Craniofacial Development.
15         3:48 pm      Gabrielle Martel (Université de Montréal, Montreal) “Epiphyseal cartilage vascular and matrix changes at sites predisposed to osteochondrosis detected by 3T MRI, second harmonic generation microscopy and histology.
4:00 pm – 4:30 pm Coffee Break (Grand salon)


4:30 pm – 5:54 pm Session 4: Musculoskeletal System IISession chairs:            Jeffrey Dixon & Yara Hosein  
16         4:30 pm      Yara Hosein (Western University, London) “Comparison of Mechanical Measures Used to Assess Orthodontic Mini-Implant Stability.  
17         4:42 pm      Emerson Krock (McGill University, Montréal) Toll-like Receptor 2 Regulates Nerve Growth Factor via NF-κB Signalling in Intervertebral Disc Cells.  
18         4:54 pm      Nicolas Anne-Archard (Université de Montréal, Montreal) “Histological characteristics of new-born foals metacarpal growth cartilage: to a better understanding of the pathophysiology of osteochondrosis.  
19         5:06 pm      Michael P Grant (McGill University, Montréal) “Ca2+ Regulates the Expression of Type II Collagen and Aggrecan in Intervertebral Disc Cells by Activating the Extracellular Calcium-Sensing Receptor.  
20         5:18 pm      Nicholas Mikolajewicz (McGill University, Montréal) “Role of exosomes released by breast cancer and myelogenous cells in stimulation of osteoclast formation by cancer-derived factors.  
21         5:30 pm      Ryan Marinovich (Western University, London) “Role of Bone Sialoprotein in the Tendon-Bone Insertion.  
22         5:42 pm      Yoon Chi (McGill University, Montréal) “CD109 inhibits TGF-beta signaling and ECM protein production in human chondrocytes.  
7:30 pm Gala Dinner – at “the Cercle” (fourth floor of Desjardins Building)
Guest speaker: François A Auger (Director, Centre de recherche en organogénèse expérimentale de l’Université Laval /LOEX)

Saturday, May 30, 2015

8:00 am – 9:00 am Breakfast (Grand salon)
9:00 am – 10:06 am Session 5: Tissue Engineering and Biomaterials ISession chairs:            Julie Fradette & Meryem Safoine
9:00 am – 9:30 am Invited Speaker: Robert Gauvin (Université Laval, Québec, QC)“Functional tissue engineering: Optimization of the ECM architecture through microfabrication and bioreactor technologies
23          9:30 am      Maxime Picard-Deland (Université Laval, Québec)“Self-Assembled Tubular Heart Valves from Human Fibroblasts.
24          9:42 am      Corey Sermer (University of Toronto, Toronto)“Platelet rich plasma enhances the integration of bioengineered articular cartilage with native tissue.
25          9:54 am      Amélie Morissette (Université Laval, Québec)“A Reconstructed Urethra by Tissue Engineering: In Situ Grafting in Rabbits for Proof of Concept.
10:06 am – 10:48 am Coffee Break and Poster viewing (Grand salon)
10:48 am – 12:00 am Session 6: Tissue Engineering and Biomaterials IISession chairs: -Jake Bedore
26        10:48 am      Derek H Rosenzweig (McGill University, Montreal)“Nucleus pulposus and chondrocyte cell growth and tissue deposition on 3D-printed scaffolds.
27        11:00 am      Bastien Paré (Université Laval, Québec)“Early detection of extracellular matrix disorganization and cytoplasmic accumulation of TDP-43 in tissue-engineered skins derived from ALS patients: an optimized approach to recover secreted proteins for biomarker discovery.
28        11:12 am      Vanessa Bianchi (University of Toronto, Toronto)“Articular Cartilage Tissue Engineering with Redifferentiated Human Chondrocytes.
29        11:24 am      Caroline Loy (Université Laval, Québec)“Tri-Culture of Vascular Cells from Cellularised Collagen-based Scaffolds Promotes Vascular Tissue Remodeling.
30        11:36 am      Julien Tremblay Gravel (McGill University, Montréal)“The culture of Nucleus Pulposus Cells on a continuously expanding culture surface enhances their phenotype for tissue engineering purposes.
31       11:48 pm      Kiefer Thouin (Université Laval, Québec) “Study of the impact of glycation in wound healing using a tissue-engineered skin.
12:00 am – 2:00 pm Lunch and poster session II (Evaluation for odd number posters only)- Grand Salon
2:00 pm – 3:30 pm Session 7: Connective Tissue Remodeling IIISession chairs:            Dieter Reinhardt & Heena Kumra
2:00 pm – 2:30 pm Invited Speaker: Chris Overall (University of British Columbia, Vancouver, BC)           « New Biological Roles for MMPs Revealed by Proteomics of the ECM in vivo»
32         2:30 pm      Beatriz Noé (Université de Montréal, Montreal)“Development of a biomarker for osteoarthritis: Cathemsin K degradation of cartilage.
33         2:42 pm      Ali Virk (McGill University, Montreal) “LPS-Induced Inflammation Inhibits Bone Repair.
34         2:54 pm      Abdualltef Alrashoudi (McGill University) “Calcium suppresses parathyroid hormone-related peptide-induced synthesis of aggrecan and type II collagen in osteoarthritic chondrocytes.
35         3:06 pm      Muhammad Naji I Albesher (McGill University, Montreal) “Degeneration of Articular Cartilage is mediated by Calcium and the Extracellular Calcium-Sensing Receptor in Osteoarthritis.
36         3:18 pm      Rahul Gawri (University of Toronto, Toronto) “Enhancing Nucleus Pulposus Tissue Formation In-Vitro: A Novel Approach.
3:30 pm – 4:00 pm Coffee Break (Grand salon)
4:00 pm – 5:30 pm Session 8: Cell – Extracellular Matrix InteractionsSession chairs:            Anie Philips & Yoon Chi
4:00 pm – 4:30 pm Invited Speaker: Darius Bägli (University of Toronto, Toronto, ON)« Urinary bladder smooth muscle-matrix interactions: molecular and epigenetic insights »
37         4:30 pm      Ingrid Saba (Université Laval, Québec)“Development of a three-dimensional (3D) cell culture model that mimics female genital mucosae.
38         4:42 pm      Iris Boraschi-Diaz (McGill University, Montreal) Regulation of osteoclast formation by collagen type I degradation products.
39         4:54 pm      Salah Boudjadi (Université de Sherbrooke, Sherbrooke) Pro-proliferative α1 integrin subunit over-expression is regulated by the c-MYC oncogenic factor in colorectal cancer cells.
40         5:06 pm      Dieter P Reinhardt (McGill University, Montreal)“Fibrillin-1 interaction with cells regulates microRNAs.
41         5:18 pm      Husam Almajed (McGill University, Montreal)“Comparison between osteoarthritic and osteonecrotic bone marrow-derived mesenchymal stem cells: Differences in the expression of the extracellular calcium-sensing receptor and osteogenesis.
5:30 pm – 6:00 pm CCTS General Assembly Meeting (for all members)Oral presentation, poster and travel awards announcementsClosing Remarks

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