Program
Click CCTC 2016 Program to download the program as PDF file.
WEDNESDAY JUNE 1, 2016
6:00-9:00 Registration, Reception and Light Dinner
University Club of McMaster, Alumni Memorial Hall
THURSDAY JUNE 2, 2016
Michael G DeGroote Centre for Learning and Discovery (MDCL) Room 1110
7:45-8:30 Deluxe Continental Breakfast
7:45-3:00 Registration desk open (MDCL foyer, outside 1110)
8:30-8:45 Welcome Remarks
Carl Richards, McMaster University, Hamilton, Ontario, Canada
BONE, CARTILAGE AND DISEASE: FUNDAMENTAL ASPECTS
8:45-9:25 Keynote Speaker: Ben Alman, Duke University, Durham, North Carolina, USA
“Rejuvenation of fracture repair: it’s all in the blood”
9:25-10:30 Bone Cell Biology and signaling – Selected Abstracts (A) presenters:
Esmail, Sally: Mapping functional domains of v-atpase a subunit: potential therapeutic target for osteoporosis and cancer metastasis
Alotaibi, Mohammed: Evaluation of bone healing in xylt-2 knockout mouse model
Zhang, Lucia: Effects of osteoblast-specific gαs over-expression on skeletal development using a transgenic mouse model
Kim, Brandon H: Extracellular atp potentiates calcium signaling by parathyroid hormone through two distinct mechanisms
Chu, Anh: Elucidating the role of lipid binding domains in v-atpases a subunits
10:30-10:45 Break
10:45 Matrix proteins/MMPs structure/function
10:45- 11:25 Invited speaker: Drew Rowan, University of Newcastle, UK
“Chondrocyte Biology in OA”
11:25-12: 15 ECM Protein-protein interactions – Selected Abstracts (B) presenters:
Hubmacher, Dirk: Adamts17, an extracellular protease with unusual biochemical properties, binds to fibrillin microfibrils
O’Hagan-Wong, Kelsey: The role of gingipains in the degradation of dentogingival attachment proteins
Alabdulkarim, YA: Serum levels of amino terminal propeptide of type 1 procollagen (p1np) as a biomarker to assess bone regeneration
Kumra, Heena: Interplay between cellular and plasma fibronectin in maintaining vessel wall integrity and function
12:15-2:00 LUNCH (MDCL foyer southeast)
Poster viewing (MDCL foyer west)
12:15-2:00 CCTS Board Meeting (MDCL-4023)
2:00 Matrix mediators and regulation of stromal cells
2:00-2:25 Invited speaker: Lisbet Haglund, McGill University, Montreal, Quebec, Canada
“Soluble factors implicated in painful IVD degeneration”
2:25-3:15 Selected Abstracts (C) presenters:
Mukherjee, Subhendu: Role of adenylate cyclase pathway in prevention of pulmonary fibrosis
Dubey, Anisha: Il-33 and associated extracellular matrix induction by oncostatin m in murine lung is independent of il-6
Krock, Emerson: Toll-like receptor 2 activation induces degeneration of human intervertebral discs
Gawri, Rahul: Simple, silica column-based method to isolate and quantify inorganic polyphosphates from mammalian tissues
3:15-3:30 Break
BONE, CARTILAGE AND DISEASE: TRANSLATIONAL AND CLINICAL ASPECTS
3:30-4:10 Invited speaker: Rick Adachi, McMaster University, Hamilton, Ontario, Canada
“Current Treatment and Diagnostics in Osteoporosis”
4:10- 5:40 Poster Presentations and Viewing
6:00-9:00 Cocktail Reception and Formal Dinner (ticket purchase required)
University Club at McMaster Alumni Hall
FRIDAY JUNE 3, 2016
(Michael G DeGroote Centre for Learning and Discovery Room 1110)
7:45-8:45 Deluxe Continental Breakfast
8:30-10:30 Registration desk open (MDCL-foyer)
HEALING AND TISSUE FIBROSIS: MOLECULAR/CELLULAR AND CLINICAL ASPECTS OF TISSUE REPAIR AND FIBROSIS
9:00-9:45 Invited speaker: Boris Hinz, University of Toronto, Toronto, Ontario, Canada
“Basic mechanisms in tissue fibrosis”
9:45-10:50 Selected Abstracts (D) presenters:
Mohammadi, Hamid: Inelastic remodeling of collagen matrices enables remote intercellular communication: insights from experimental and computational studies
Shafieyan, Yousef: Live cell contraction studies on suft substrates: a paradigm to characterize diseased and healthy cells
Lama, Polly: Focal uncoupling of cell-matrix interactions and swelling acclerate processes leading to pain in disc degeneration
Rosenzweig, Derek H: High mechanical strain inhibits pc12 cell neurite sprouting through reduced mapk signaling and decreased neurofilament expression
Coelho, Nuno M: Discoidin domain receptor 1 enables the force-mediated collagen contraction
10:50-11:10 Break
11:10-11:55 Invited speaker: Eric White, University of Michigan, USA
“Extracellular matrix in the diagnosis and management of lung fibrosis”
12:00-1:00 LUNCH (MDCL foyer southeast)
12:50-1:50 Final Poster Viewing (MDCL foyer west)
1:50- 2:30 Selected Abstracts (E) presenters:
Ayaub, Ehab: Il-6 mediated hyperpolarization of pro-fibrotic macrophages is dependent on spliced xbp1
Auler, Markus: Posttranscriptional regulation of myofibroblast homeostasis
Bellaye, P-S: Pathogenesis of pulmonary fibrosis – the role of extracellular heat shock protein-90 (hsp90) in myofibroblast differentiation and persistence
STEM CELLS, TISSUE ENGINEERING AND REGENERATION
2:30-3:10 Invited speaker: Cheryle Seguin, Western University, London, Ontario, Canada
“From development to disease: the role of progenitor cells in the
intervertebral disc”
3:10-3:30 Break
3:30-4:10 Selected Abstracts (F) presenters:
Crasto, Gazelle J: An ultrasound temporally activated nano-system delivery implant that releases bmp-2 for on-demand bone regeneration
Clafshenkel, William P: Using human adipose stromal/stem cell-derived reconstructed osseous tissues as a platform for studying the impact of melatonin on osteogenesis
Chatoor, Kenny: Exploring the potential use of passaged nucleus pulposus cells for nucleus pulposus tissue generation in vitro
4:10-4:30 Poster Breakdown
4:30-5:30 CCTS Business Meeting/General Assembly
Conference wrap up:
Announcement of winning trainee presentations
Concluding remarks
Venues: McMaster Campus: See http://www.mcmaster.ca/welcome/campusmap.cfm
University Club in Alumni Memorial Hall (building 8 on campus map) evening events June 1 and 2
Mary Keyes residences (building 50 on map)
Scientific sessions are in MDCL (building 52 on campus map) june 2 and june 3
Oral sessions will be in MDCL room 1110, poster sessions in the MDCL Foyer (click below CAmpus Map map)
MDCL Center First Floor