CCTC 2021 Summer Blitz Series
5 minutes trainee talks followed by a 3-minute discussion period
| Session 1: Tuesday, June 29, 2021, 3pm Webinar Link | |
| Session chaired by Megan Vierhout and Pari Yazdanshenas, McMaster University | |
| Brian Wu University Health Network, University of Toronto Title: Identification of EphB4 as a critical mediator of pulmonary fibrosis | |
| Christie Costello Division of Biomedical Sciences (Genetics), Faculty of Medicine, Memorial University of Newfoundland Title: Individual participant data meta-analysis of metabolomics on refractory knee pain in primary osteoarthritis patients | |
| Gabriel Cloutier Université de Sherbrooke Title: Further characterization of the 67 kDa laminin receptor (67LR) in colorectal cancer cells | |
| Rameen Jamil McMaster University and The Research Institute of St. Joe’s Hamilton Title: Antibodies to dense fine speckled 70 autoantigen (DFS70) predicts good outcome in mechanically ventilated COVID-19 patients | |
| Hosni Cherif McGill University Title: New diagnostic and therapeutic biomarkers for human intervertebral disc revealed by single-cell RNA-seq |
| Session 2: Tuesday, July 6, 2021, 3pm Webinar Link | |
| Session chaired by Safaa Naiel, McMaster University and Christie Costello, Memorial University of Newfoundland | |
| Britney Messam Western University Title: The receptor for hyaluronan-mediated motility as a regulator of drug sensitivity in triple-negative breast cancer | |
| Sunny Shih McGill University Title: Link N suppresses periostin expression in human osteoarthritic cartilage | |
| Parichehr Yazdanshenas McMaster University Title: Characterizing circulating monocytes and profibrotic macrophages in fatal COVID-19 | |
| Cori Lau McGill University Title: Role of dietary composition in Marfan syndrome metabolism and aortic aneurysm progression | |
| Eleane Hamburger McGill University Title: Targeting senescent cancer cells using senolytic drugs to prevent breast-to-bone metastasis | |
| Session 3: Tuesday, July 13, 2021, 3pm Webinar Link | |
| Session chaired by Spencer Revill, McMaster University and Brian Wu, University Health Network, University of Toronto | |
| Syrine Arif Université Laval Title: The components of the skin wound extracellular matrix dictates the diffusion of microvesicles derived from myofibroblasts | |
| Kabriya Thavaratnam University Health Network, University of Toronto Title: Utilizing single nuclei RNA sequencing to identify distinct cell subsets and mechanisms in the synovium of early and late stage radiographic knee osteoarthritis | |
| Quan Zhou McMaster University Title: AT2 regulation through BMP signaling | |
| Megan Vierhout McMaster University Title: Characterization of the transcriptomic signature of circulating monocytes in idiopathic pulmonary fibrosis | |
| Oliver Wu Martinez McGill University Title: Synergistic effect of senolytic combination reduces intervertebral disc degeneration | |
| Session 4: Tuesday, July 20, 2021, 3pm Webinar Link | |
| Session chaired by Eleane Hamburger, McGill University and Quan Zhou, McMaster University | |
| Matthew Mannarino McGill University Title: Evaluation of o-Vanillin & RG-7112 for lower back pain in SPARC-null mice | |
| Mable Chan University Health Network, University of Toronto Title: Comparing effects of pro-inflammatory versus pro-resolving monocytes/macrophages in human ex vivo explant and in vivo murine models of knee osteoarthritis | |
| Fereshteh Sadat Younesi University of Toronto Title: DNA methylation transferase regulates mechanical myofibroblast activation of mesenchymal stem cells | |
| Alexander Noble McMaster University Title: Manipulation of the mechanotransduction pathway to attenuate lung fibrosis in idiopathic pulmonary fibrosis | |
| Sudeshna Dhar McMaster University Title: Role of CD4+ T cells in the pathogenesis of RA: Immunization with citrullinated T cell epitopes is sufficient to induce immunological and clinical manifestations of arthritis in DR4-transgenic mice | |
| Session 5: Tuesday, July 27, 2021, 3pm Webinar Link | |
| Session chaired by Matthew Mannarino, McGill University and Sudeshna Dhar, McMaster University | |
| Navdeep Kaur Bone and Joint Center, Henry Ford Health System, Detroit, MI, USA Title: Customized microRNA sequencing pipeline identifies a key microRNA in late-stage knee osteoarthritis | |
| Daniel Bisson McGill University Title: Toll-like receptors modulate bone remodelling in scoliotic facet joint osteoarthritis | |
| Maya Ezzo University of Toronto Title: Macrophage and fibroblast acute contact effects and consequences | |
| Rong-Mo Zhang McGill University Title: Genetic profiling of thoracic aortic aneurysms reveals the role of miR-122 in pathogenetic inflammatory pathways | |
| Muthu Lakshmi Muthu McGill University Title: Sex specific role of fibrillin-1 in adipose tissue development and function | |
| Session 6: Tuesday, August 3, 2021, 3pm Webinar Link | |
| Session chaired by Maya Ezzo, University of Toronto, and Vaishna Kumaran, McMaster University | |
| Neha Dinesh McGill University Title: Elucidating the role of fibronectin isoforms in skeletal development and in spondylometaphyseal dysplasia | |
| Emily Ha University of Toronto, University Health Network Title: Higher mid-tibia bone marrow adiposity is associated with an increased risk of incident fractures over 5-years: the AMBERS cohort study | |
| Salem Werdyani Memorial University of Newfoundland Title: Novel genes found to be associated with osteoarthritis by whole exome sequencing analysis | |
| Mina Vaez University of Toronto Title: Impact of Collagen crosslinking on biophysical properties of collagen and tissue functionality | |
| Session 7: Tuesday, August 10, 2021, 3pm Webinar Link | |
| Session chaired by Neha Dinesh, McGill University and Alexander Noble, McMaster University | |
| Li Li McGill University Title: o-Vanillin combined with human mesenchymal stem cells regenerates symptomatic degenerate disc cells | |
| Gargi Goel McGill University Title: Biofabrication and tissue engineering approaches for enhanced ligament reconstruction | |
| Safaa Naiel McMaster University Title: Characterizing the pulmonary microenvironment and macrophage phenotype in pulmonary Langerhans cell histiocytosis | |
| Sahar Samani McGill University Title: Transglutaminase 1 – a novel factor regulating osteoclastogenesis? | |
| Industry Guest Speaker: Alison Cappadocia (MSL) Boehringer Ingelheim Title: From academic to pharma – My journey from PhD to MSL | |