Return to CCTC 2025

Scientific Program

Download the complete program booklet: CCTC 2025 Program Booklet

DATE / TIME

EVENT DETAILS

DAY 1

Monday, May 26th, 2025 | Workshop Day
Venue: New Residence Hall Ballroom
3625 Avenue du Parc, Montréal, (Québec) H2X 3P8

7:15-8:15

Registration: Badge Pick-up | Continental Breakfast | Poster Set-up
New Residence Hall Ballroom – Atrium

8:15-8:30

Welcome Remarks [CCTC 2025 Co-Chairs]: Dr. Rahul Gawri, MD, Ph.D. (McGill University) & Dr. Chan Gao, MD, Ph.D. (McGill University)
New Residence Hall Ballroom

8:30-10:30

WORKSHOP SESSION 1a: Navigating Conflicts, Bullying, Harassment, and Microaggressions: One-on-One Negotiation Tactics
Session Leads: Huong Le Hollie Bui, PhD Candidate (Desautels Faculty of Management, McGill University); Dr. Rahul Gawri, MD, Ph.D. (McGill University), Dr. Naser Muja, Ph.D., MBA (McGill University).

10:30-10:45

Coffee break

10:45-12:45

WORKSHOP SESSION 1b: Managing Conflicts, Bullying, Harassment, and Microaggressions: Tactics to Negotiate with Other Team Members and the Role of Leadership
Session Leads: Huong Le Hollie Bui, PhD Candidate (Desautels Faculty of Management, McGill University); Dr. Rahul Gawri, MD, Ph.D. (McGill University), Dr. Naser Muja, Ph.D., MBA (McGill University).

12:45-14:15

Lunch and Poster Viewing

14:15-16:15

WORKSHOP SESSION 2: Building High-Performing and Inclusive Teams Through Productive Conflict 
Session Leads: Anna-Maria Broomes, PhD Candidate (Desautels Faculty of Management, McGill University); Dr. Chan Gao MD, Ph.D. (McGill University); Dr. Naser Muja, Ph.D., MBA (McGill University).

16;15-16:30

Coffee Break

16:30-17:30

Reflections, Panel Discussions, and Closing Remarks

17:30-19:30

Welcome and Networking Reception

DAY 2

Tuesday, May 27th, 2025 | Scientific Sessions
Venue: New Residence Hall Ballroom
3625 Avenue du Parc, Montréal, (Québec) H2X 3P8

7:30-8:30

Registration: Badge Pick-up | Continental Breakfast | Poster Set-up
New Residence Hall Ballroom – Atrium

8:30-8:45

Welcome Remarks: Dr. Rahul Gawri & Dr. Chan Gao (CCTC 2025 Co-Chairs)
New Residence Hall Ballroom

8:45-10:15

SESSION 1: Cell Biology of Connective Tissues
Session Chairs: Dr. Matthew Grol, Ph.D.; Western University and Mariia Meilkozorova, University of Alberta

8:45-9:15

Keynote Speaker: Dr. Dieter Reinhardt, Ph.D.; McGill University
Title of the Talk: Key Matrix Proteins in Connective Tissue Development and Disease

9:15–9:25

Special Session: Loeys-Dietz Syndrome Foundation Canada: Dr. Jida El Hajjar, Ph.D.; Executive Director, Loeys-Dietz Syndrome Foundation Canada
Title of the Talk: From Rare to Recognized: Building a National Response to Loeys-Dietz Syndrome (LDS) and Heritable Thoracic Aortic Disease (HTAD)

9:25–9:40

Title of the Talk: Exploring the relationship between TGFβ and mitochondrial function in chondrocytes
Presenter: Emily White (Beier Lab, Western University)

9:40–9:55

Title of the Talk: Metabolic Stress Disrupts Synovial Macrophage-Fibroblast Communication Enhancing Fibroblast Activation in Osteoarthritis
Presenter: Garth Blackler (Appleton Lab, Western University)

9:55–10:10

Title of the Talk: Fibrillin-1 regulates extracellular matrix-driven adipose tissue differentiation and affects overall body metabolism
Presenter: Iram Fatima Siddiqui (Reinhardt Lab, McGill University)

10:10–10:25

Title of the Talk: Transcriptomic Differences in Adipocytes, Macrophages and Endothelial Cell Populations of Infrapatellar Fat Pads from Patients with Knee Osteoarthritis
Presenter: Keemo Delos Santos (Kapoor Lab, University of Toronto)

10:25-10:40

Coffee break

10:40-12:00

SESSION 2:Bioprinting and Additive Manufacturing in Connective Tissue Biology
Session Chairs: Dr. Derek Rosenzweig, Ph.D.; McGill University and Tarek Klaylat, McGill University

10:40–11:10

Keynote Speaker: Dr. Houman Savoji, Ph.D.; Université de Montréal (UdeM).
Title of the Talk: Advanced Biofabrication of Functional Biomaterials for Cardiac Tissue Engineering and Heart-On-Chip Applications

11:10 –11:25

Title of the Talk: Synergistic Effects of Bottlebrush Polymers and Hyaluronic Acid in Alleviating Friction Damage
Presenter: Duy Anh Pham (Banquy Lab, Université de Montréal)

11:25–11:40

Title of the Talk: Targeting cancer senescence in 3D models of tumor-bone metastases
Presenter: Mansoureh Mohseni Garakani (Rosenzweig Lab, McGill Univ.)

11:40–11:55

Title of the Talk: Examining the effects of glycosaminoglycans in a tissue-based in vitro model of biomimetic collagen mineralization
Presenter: Rachel Lau (Sone Lab, University of Toronto)

11:55–12:10

Title of the Talk: Bioinspired Hybrid System for Targeted Therapy and Friction Reduction in Osteoarthritic Cartilage
Presenter: Changsheng Wang (Banquy Lab, Université de Montréal)

12:10–13:30

Lunch and Poster Judging – Session 1 | Canadian Connective Tissue Society (CCTS) Board Meeting (Board Members Only)

13:30-15:00

SESSION 3: Clinical Perspectives in Connective Tissue Pathobiology
Session Chairs
: Dr. Mark McKee Ph.D.; McGill University and Lynn Huong, Western University

13:30-14:00

Keynote Speaker: Dr. Gustavo Duque, MD, FRCPC; McGill University
Title of the Talk:  Muscle-Bone Crosstalk: Mechanisms and Implications for Connective Tissue Health

14:00–14:15

Title of the Talk: Oral delivery of delta-9-tetrahydrocannabinol has pain-modifying effects in mouse models of knee osteoarthritis
Presenter: Behdad Ravarian (Kapoor Lab, University of Toronto)

14:15–14:30

Title of the Talk: Cephalometric analysis of a new dominant osteogenesis imperfecta IFITM5 mouse model.
Presenter: Dr. Hadil Al-Jallad (Moffatt Lab, Shriners’ Hospital, Montreal)

14:30–14:45

Title of the Talk: Exploring the Roles of RANK/RANKL and OPG in Mammalian Physiology: A Scoping Review of Functions Beyond the Skeletal System
Presenter: Mariia Mielkozorova (Komorova Lab, University of Alberta)

14:45–15:00

Title of the Talk: Modulation of Endothelial Function by Low-Dose Aspirin and Its Implications for Avascular Necrosis
Presenter: Avesta Gheysari (Chantal Séguin Lab, McGill University)

15:00-15:15

Coffee Break

15:15-16:45

SESSION 4: Functional Biomaterials for Connective Tissue Repair
Session Chairs: Dr. Marc Lavertu, Ph.D.; Université de Montréal (UdeM) and Laura Mélanie Bouret, Université de Montréal (UdeM)

15:15-15:45

Keynote Speaker: Dr. Xavier Banquy, Ph.D.; Université de Montréal (UdeM)
Title of the Talk: A Bioinspired Approach for the Design of an Artificial Synovial Fluid

15:45–16:00

Title of the Talk: Mesendodermal progenitors in Combination with a Synthetic Hydrogel (NPGEL) in a Sheep Model of Low Back Pain: a Safety Study
Presenter: Paolo Brigato (Vincenzo Lab, Università Campus Bio-Medico di Roma)

16:00–16:15

Title of the Talk: Developing N-Acetylcysteine Electrospun Scaffolds for Articular Cartilage Treatment
Presenter: Dr. Anthony Callanan (The University of Edinburgh)

16:15–16:30

Title of the Talk: Exploring the effects of selected extracellular matrix fragments on adipogenic and angiogenic processes for tissue engineering applications
Presenter: Elias Cuartas-Gomez (Fradette Lab, Université Laval)

16:30–16:45

Title of the Talk: 3D Ultrastructural Mapping of Collagen Across Entire Thickness of Zebrafish Corneal Stroma
Presenter: Dr. Natalie Reznikov (McGill University)

18:00-22:30

Welcome Reception and Gala Dinner of the 29th Canadian Connective Tissue Conference (CCTC)
Heritage Hall, McGill Faculty Club
3450 McTavish, Montréal, QC, H3A 1X9

Celebrating: All the attendees of the 29th Canadian Connective Tissue Conference (CCTC)

Lifetime Achievement Award Winner: Dr. Frank Beier, Ph.D.
Title of the Talk: 35 years of cartilage research – what a journey it has been…

Robin Poole Investigator Award Winner: Dr. Lisbet Haglund, Ph.D.
Title of the Talk: My Path from Cell-Matrix Interactions to Senolytics in Back Pain Research

Musical Performance by: Every Other Wednesday
Band Members: Dr. Derek Rosenzweig, Ph.D.; Dr. Kenneth Finnson, Ph.D.; Dr. Mike Shulha, Ph.D.; and Dr. Carly Sweeney, Ph.D.   

DAY 3

Wednesday, May 28th, 2025 | Scientific Sessions
Venue: New Residence Hall Ballroom
3625 Avenue du Parc, Montréal, (Québec) H2X 3P8

7:30-8:30

Continental Breakfast
New Residence Hall Ballroom – Atrium

8:30-8:45

Opening Remarks: Dr. Rahul Gawri, MD, Ph.D. (McGill University) & Dr. Chan Gao, MD, Ph.D. (McGill University)
New Residence Hall Ballroom

8:45-9:15

SESSION 5: Matrix Biology in Connective Tissue Research
Session Chairs: Dr. Anie Philip, Ph.D.; McGill Universityand Gopeekrishnan Unnithan, McGill University

8:45-9:15

Keynote Speaker: Dr. Julie Fradette, Ph.D.; Université Laval
Title of the Talk: The Power of Tissue Engineering: The Interplay Between Cells and Extracellular Matrix

9:15–9:30

Title of the Talk: CD109 at the Helm: A Critical Regulator of Inflammation and Fibrosis in the Skin
Presenter: Adel Batal (Philip Lab)

9:30–9:45

Title of the Talk: Extracellular Matrix Remodeling in the Doral Root Ganglia as a Regulator of Pain
Presenter: Allutas Alhamwi, (Krock Lab, McGill University)

9:45–10:00

Title of the Talk: Matrix Gla Protein Expression in Pericytes and Myofibroblasts Contributes to Renal Fibrosis
Presenter: Kyoungmi Bak (Murshed Lab, McGill University)

10:00–10:15

Title of the Talk: Laminin Receptors Integrin β1 and Dystroglycan are Critical for the Regulation of Muscle Stem Cells
Presenter: Simon Dumontier (Bentzinger Lab, Université Sherbrooke)

10:15-10:30

Coffee Break

10:30-12:00

SESSION 6: Repair and Regeneration of Biomechanically Loaded Tissues: Novel Approaches for Intervertebral Discs, Menisci, and Tendons
Session Chairs: Dr. Roman Krawetz, Ph.D.; University of Calgary and Xin Song, University of Toronto

10:30-11:00

Keynote Speaker: Dr. George Dodge, Ph.D.; CEO, Mechano Therapeutics LLC
Title of the Talk: Mechano-sensitive musculoskeletal drug delivery: Is it all is cracked up to be?

11:00–11:15

Title of the Talk: Senotherapeutics Prevent Disc Degeneration and Back Pain
Presenter: Saber Ghazizadeh (Haglund Lab, McGill University)

11:15–11:30

Title of the Talk: Priming human bone marrow-derived mesenchymal stem cell metabolism using physioxia and physiological glucose concentrations for ligament tissue engineering
Presenter: Tarek Klaylat (Gawri Lab, McGill University)

11:30–11:45

Title of the Talk: Distinct Purinergic Receptors Mediate Exogenous Nucleotide-induced Calcium Signalling and Gene Expression Changes in Tenocytes
Presenter: Ryan Armstrong (Grol Lab, Western University)

11:45–12:00

Title of the Talk: Finite Element Modeling of Electroarthrography for the Non-Invasive Detection of Cartilage Quality
Presenter: Peter Suderman (Changoor Lab, University of Toronto)

12:00-13:30

Lunch and Poster Judging – Session 2

13:30-15:00

SESSION 7: Bone Biology and Tissue Mineralization
Session Chairs: Dr. Showan Nazhat, Ph.D.; McGill University and Elias Cuartas-Gomez, Université Laval

13:30-14:00

Keynote Speaker: Dr. Monzur Murshed, Ph.D.; McGill University
Title of the Talk: Vascular Calcification and Matrix Gla Protein: Insights from Genetic Models

14:00–14:15

Title of the Talk: Retinoid signaling modulates ectopic calcification of annulus fibrosus cells in a mouse model of DISH
Presenter: Alexander Rico (Séguin Lab, Western University)

14:15–14:30

Title of the Talk: Trabecular bone formation in vitro by the OmGFP66 osteogenic cell line
Presenter: Benazir Khurshid (McKee Lab, McGill University)

14:30–14:45

Title of the Talk: Galectin 3 is upregulated in the muscle with heterotopic ossification (HO) induced by spinal cord injury (SCI)
Presenter: GopeeKrishnan Unninanthan (Gao Lab, McGill University)

14:45–15:00

Title of the Talk: Understanding preferential gap zone collagen mineralization in vitro
Presenter: Liyang Zhong (Sone Lab, University of Toronto)

15:00-15:15

Coffee Break

15:45-17:15

Session 8:Cartilage Biology and Pathobiology
Session Chairs: Dr. Fackson Mwale, Ph.D.; McGill University and Hayley Murray, Western University

15:45-16:15

Keynote Speaker: Dr. Adele Changoor, Ph.D.; University of Toronto
Title of the Talk: Electroarthrography: Advancing Cartilage Electromechanics for Non-invasive Monitoring of Joint Health

15:45–16:00

Title of the Talk: Synovial myeloid subtypes in knee joint health, injury and osteoarthritis
Presenter: Geneva Herold (Appleton Lab, Western University)

16:00–16:15

Title of the Talk: Fibroblast and Myeloid Cells with High Mitochondrial Content Represent Biologically Significant Populations within the OA Synovium
Presenter: Wesley Tran (Grol Lab, Western University)

16:15–16:30

Title of the Talk: Comparing naturally occurring OA between equine and human cartilage
Presenter: Maria Bikuna (Biomomentum Inc., Montréal)

16:30–16:45

Title of the Talk: Spatial Transcriptomics of Joint Space-Interfacing Tissues Using a Pre-Clinical Mouse Model of Osteoarthritis
Presenter: Brandon Vaz (Kapoor Lab, University of Toronto)

16:15-18:00

General Assembly and Awards Presentation

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